Conclusions: The inadequate dose of OAM in opioid substitution treatment for opioid-dependent patients seems to be related to the misuse of benzodiazepines.
(C) 2009 Lippincott Williams & Wilkins, Inc. (Source: Addictive Disorders & Their Treatment)
The complex and unpredictable series of symptoms that comes with the terminal stage of neoplastic disease significantly compromises patients’ quality of life, and poses harsh therapeutic challenges for clinicians. Good control of severe cancer-related cholestatic pruritus seems to be hard to achieve and pruritus still undermines the remaining physical and relational capabilities of seriously ill cancer patients. Its pathogenesis remains substantially unknown and its treatment mostly empirical. (Source: Journal of Pain and Symptom Management)
Author: setmefree Posted: Sun Aug 23, 2009 10:22 pm Welcome Bigdogg! So glad you are feeling so much better! Isn’t it wonderful!!?? I have been on Sub for about 6 weeks and they have been the best I’ve had in a long time. I agree with Diary on the headaches/nausea. I had some headaches and read on this forum about spitting out the stuff after pill is good and dissolved and worked immediately! Keep up the good work! (Source: Suboxone Forum)
Author: Diary of a Quitter Posted: Sun Aug 23, 2009 10:00 pm Hi Chris, welcome to the forum. Unfortunately, I don’t have any firsthand experience with switching from methadone to suboxone. I have heard Dr. Junig say that 30mgs of Methadone is an ok dose to switch from. Anything higher and the sub wouldn’t be strong enough to keep you out of withdrawal. I also don’t know about the weight. I have heard people say they’ve gained weight on sub. I gained about 15 pounds…but that’s probably because I didn’t eat when I was on my DOC. I guess it’s likely that everyone is different. Oh, my kid just got hurt, gotta go. (Source: Suboxone Forum)MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed – updated hourly from thousands of authoritative health and news sources.
Author: shelwoy Posted: Sun Aug 23, 2009 6:33 pm Greg- Hello and welcome to the forum. There is nothing wrong with the ideology of your dosing scenario, you are 100% correct, we are not all the same and what works for one does not necessarily work for another. In regards to the majority, there are valid reasons I personally ( I cannot speak for anyone else here) mention finding the lowest dose possible to find comfort in.First, there is the pharmacology which states, “The agonist effects of buprenorphine increase linearly with increasing doses of the drug until at moderate doses they reach a plateau and no longer continue to increase with further increases in doseâÂ?Â?the âÂ?Â?ceiling effect.In fact, in high doses and un…
Author: billyklez Posted: Sun Aug 23, 2009 5:22 pm Hello …. Thanks for the wonderful, welcoming, and sympathetic reply. I feel a lot better about jumping into this forum. Regarding the “fake/pseudo-withdrawal” issue, I sort of figured that’s what you meant. But I didn’t want to assume or infer without clearing it up. INdeed, it’s a real experience, one that demands attention. And I respect the ways people choose to contend with that experience, including the choice to use an illicit substance. As a harm reductionist, I advocate “any positive change as defined by the person” … no judging, meet people where they’re at, no preaching, no browbeating, no coaxing or cajoling or selling, and basically doing whatev…
Author: Diary of a Quitter Posted: Sun Aug 23, 2009 4:38 pm Maybe you could just try taking a lower dose. 16mgs is a lot. Many people can get by with a lower dose for maintenance purposes – like 4mg or even 2mgs; I found that staying at a lower dose eliminated most of the side effects that I was experiencing. Then you can take your time tapering off. I really don’t recommend tapering off suboxone quickly. If you still have pain you need to find some way to manage it. Otherwise it will always be a trigger for relapse. Good luck, and it might be smart to talk all of this over with your doctor. (Source: Suboxone Forum)
Author: capecodmom Posted: Sun Aug 23, 2009 3:46 pm Hi guys, my name is Jen, I’m so glad that I found this board. I was so surprised when I saw a whole topic discussing the way to take suboxone. I am on 16mg and have just been break them in half or quarters, putting them under my tongue, swallowing whenever I felt the need, drinking at the same time. Now I am finding out that I might not be getting my full dose because I have been doing it this way? Is that really true that you shouldn’t drink anything or even swallow while the pills are dissolving? (Source: Suboxone Forum)
Author: Diary of a Quitter Posted: Sun Aug 23, 2009 12:47 pm I can’t get the link to work. (Source: Suboxone Forum)MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed – updated hourly from thousands of authoritative health and news sources.
Author: Diary of a Quitter Posted: Sun Aug 23, 2009 12:40 pm It takes 37.5 hours for a dose of suboxone to reduce by half in your bloodstream. So if you take 8mgs at 8am on Monday, you’d still have 4mgs in your body at 9:30pm on Tuesday. And that’s without even taking another dose. So when you take your second 8mgs on Monday night, the doses are stacking up in your bloodstream. On top of that, buprenorphine, the active ingredient in suboxone, has a ceiling effect. It’s very potent at low doses. After about 4mgs, it doesn’t get any stronger – the higher dose we take for addiction treatment is to make it last longer and because it discourages relapse. The buprenorphine occupies all of your opiate receptors, so even if you do relapse,…